Friday, May 9, 2025

Health Technology

Proteomic profiling of primary cilia in the developing brain uncovers new regulators of cortical development

AbstractIn the developing brain, the primary cilia of radial glial cells extend from the surface of the lateral ventricle, serving as the signaling hub...

Adaptations in common synaptic inputs to spinal motor neurons during grasping versus a less functional hand task

AbstractPrevious evidence suggests that shared synaptic inputs across spinal motor neurons play a key role in coordinating multiple muscles during hand movements, reducing control...

The FAIIR conversational AI agent assistant for youth mental health service provision

Study design and settingThe study comprised two phases. The first phase involved building FAIIR for the identification of issue(s) that a young person might...

How AIOps Can Help Healthcare IT Teams

As an organization’s IT environment grows, so does its need to efficiently manage data, applications, networks and other intricate components of modern systems. Many organizations...

Artificial neural networks date back to the 1950s – now they’re ready to transform healthcare

Unlike their more modern large language model counterparts, artificial neural networks require human input to learn and function. ANNs have been around since the 1950s....

Integrating simulated and experimental data to identify mitochondrial bioenergetic defects in Parkinson’s Disease models

AbstractMitochondrial bioenergetics are vital for ATP production and are associated with several diseases, including Parkinsons Disease. Here, we simulated a computational model of mitochondrial...

Computational design of conformation-biasing mutations to alter protein functions

AbstractNearly all proteins undergo conformational changes to perform their biological functions. Intentional manipulation of conformational occupancy could produce novel or altered protein functions. We...